Electrical impedance for drug discovery & cell viability
Label-free, quantitative, real-time readouts for cytotoxicity, viability and dose–response — ready for high-throughput screening.
For: Cardiac safety screening · Cytotoxicity & viability · Dose–response profiling
Which situation fits your project best?
Every workflow starts somewhere different. Pick the scenario that matches what you’re trying to do — we’ll route you to the right hardware, adapter and reference design.
Label-free pharmacology readouts
Monitor cytotoxicity, cell viability and dose–response continuously, without labels or stains. Capture kinetics that endpoint assays miss — early apoptosis, recovery, secondary effects.
Multi-well & automated fluidics
Easily interface with standard plate formats and automated fluidics. Compatible with 96- and 384-well workflows for industrial pharmacology screens.
Scalable screening throughput
From benchtop systems to large-scale screening platforms, with seamless channel expansion. Combine with MEArack for high-density biochip readouts in compound libraries.
Not sure which fits? Talk to an engineer — we’ll map your assay to the right hardware in one call.
Stop guessing between endpoints.
Start monitoring continuously.
Most cell assays force you to pick between staining, dilution and endpoint readouts. Impedance gives you a continuous, label-free signal in the same well — without disturbing the sample.
Cardiac safety screening
Cardiac safety screening
Cytotoxicity & viability
Cytotoxicity & viability
Dose–response profiling
Dose–response profiling
Drug delivery research
Drug delivery research
How impedance translates biology into data
Different impedance regimes report on different biological features. Combine them and you get a structural and functional fingerprint in a single sweep.
Label-free pharmacology readouts
Monitor cytotoxicity, cell viability and dose–response continuously, without labels or stains. Capture kinetics that endpoint assays miss — early apoptosis, recovery, secondary effects.
Multi-well & automated fluidics
Easily interface with standard plate formats and automated fluidics. Compatible with 96- and 384-well workflows for industrial pharmacology screens.
Scalable screening throughput
From benchtop systems to large-scale screening platforms, with seamless channel expansion. Combine with MEArack for high-density biochip readouts in compound libraries.
High-throughput cardiac safety screening at 1 ms resolution
A Sciospec OEM architecture powers simultaneous impedance (contractility) and extracellular field potential (EFP) recordings for CiPA-compliant cardiac safety screening.
Challenge
High-throughput cardiac safety screening needs physiological fidelity — impedance and EFP must be captured together, without electromechanical dissociation.
Sciospec role
Sciospec delivered a validated measurement core combining EIS and EFP at 1 ms temporal resolution, scalable from 96 to 576+ channels.
Result
Partners can run robust, automated CiPA-compliant drug screening on the same platform they use for assay development.
Why it matters
Speed alone is not screening. Simultaneous, synchronized readouts are what make the throughput scientifically meaningful.
EIS Analyzer
The measurement architecture behind pharmacology & drug discovery
Impedance-based analytics offer a powerful, label-free tool for modern pharmacology — providing real-time, quantitative insights into cellular behaviour, drug efficacy and toxicological response. Sciospec platforms meet the evolving demands of drug-development workflows, from early research to high-throughput screening.
Covers: Label-free pharmacology readouts · Multi-well & automated fluidics · Scalable screening throughput
Cardiac safety screening
Discuss your project with our team
Get in touch with us
Phone
Headquarters
Sciospec Scientific Instruments GmbH
Leipziger Str. 43b
04828 Bennewitz, Germany
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